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Global Serum-free Media Market to reach USD 3.9 billion by the end of 2030

Global Serum-free Media Market Size study & Forecast, by Product (CHO Media, HEK 293 Media, BHK Media, Vero Medium, Stem Cell Medium, Other Serum-free Media), by Application (Biopharmaceutical Production, Monoclonal Antibodies, Vaccines Production, Tissue Engineering & Regenerative Medicine, Other Therapeutic Proteins), by Type (Liquid Media, Semi-Solid & Solid Media), by End-User (Pharmaceutical & Biotechnology Companies, Research & Academic Institutes, Other End-Users) and Regional Analysis, 2023-2030

Product Code: HLSB-53738170
Publish Date: 10-08-2023
Page: 200

Global Serum-free Media Market is valued approximately at USD 1.46 billion in 2022 and is anticipated to grow with a healthy growth rate of more than 13.03% over the forecast period 2023-2030. Serum-free media contains proper ratios of nutrients and hormones because they don’t require animal serum for cell growth. Serum-free media for cell culture has a number of advantages, including increased productivity and consistency as well as easier purification and downstream processing. In addition, serum-free media formulations can contain combinations of selective growth agents for specific cell types. Serum-free medium formulations are available for many primary cultures and cell lines, including hybridoma cell lines, Chinese hamster ovary (CHO) lines that produce recombinant proteins, and cell lines that act as hosts for virus production (e.g., 293, VERO, MDCK, MDBK). The market growth of serum-free media is driven by factors such as rising focus on cell-based therapeutics, growing production of new biopharmaceuticals and large scale manufacturing with CHO cells in cell culture.

According to Statista, the global cell culture market reached around USD 19.2 billion in 2022 and it is expected that by 2030, the market would be worth more than USD 33 billion, with a CAGR of 7.2%. More FDA approvals, clinical trials, and strategic initiatives such collaborations by the key market players is expanding the market. Moreover, increasing funding in stem cell research and rising awareness of media-based diagnostic testing may create abundant opportunities for the market in the forecast years. In September 2021, the California Institute for Regenerative Medicine awarded Stanford physician-researchers almost USD 31.0 million to begin the first-in-human stem cell clinical trials for the treatment of heart failure, stroke, and a specific form of spinal cord and brain tumor. However, the high cost of production process and high research and Development costs may stifle market growth throughout the forecast period of 2023-2030.

The key regions considered for the Global Serum-free Media Market study includes Asia Pacific, North America, Europe, Latin America, and Middle East & Africa. North America dominated the market in 2022 with largest market share due to the existence of a strong R&D infrastructure and a supportive regulatory environment, both of which are quickly changing to accommodate the sector’s continual scientific advancement. For instance, in November 2022, FUJIFILM Holdings Corporation invested USD 188.0 million in Research Triangle Park (RTP), North Carolina, to construct a manufacturing plant for serum-free media. However, Asia Pacific is expected to be the fastest growing region during the forecast period, due to more R&D and clinical trial programs for chronic and serious illnesses every year.

Major market player included in this report are:
Sartorius AG
FUJIFILM Holdings Corporation
Lonza Group AG
STEMCELL Technologies
PromoCell GmbH
Thermo Fisher Scientific Inc.
Corning Incorporated
FUJIFILM Irvine Scientific
Athena Environmental Sciences
Sartorius CellGenix

Recent Developments in the Market:
Ø In November 2022, BioPharma Dynamics expanded their product range for the Gene & Cell Therapy sector to offer a range of serum-free and chemically specified cell medium solutions. The selection of cell media products comprises cell cryopreservation solutions, stem cell media, and immune cell media, all of which are appropriate for cell therapy applications.
Ø In August 2022, Thermo Fisher Scientific Inc. expanded the cell culture media manufacturing plant in Grand Island, New York in order to enable the production of fresh vaccines and biologics.
Ø In July 2022, Moderna, Inc. and Thermo Fisher Scientific Inc. entered a 15-year strategic collaboration agreement in order to facilitate the dedicated large-scale manufacturing of Spikevax, Moderna’s COVID-19 vaccine, and other investigational mRNA therapies in its pipelines in the United States.

Global Serum-free Media Market Report Scope:
ü Historical Data – 2020 – 2021
ü Base Year for Estimation – 2022
ü Forecast period – 2023-2030
ü Report Coverage – Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
ü Segments Covered – Product, Application, Type, End-User, Region
ü Regional Scope – North America; Europe; Asia Pacific; Latin America; Middle East & Africa
ü Customization Scope – Free report customization (equivalent up to 8 analyst’s working hours) with purchase. Addition or alteration to country, regional & segment scope*

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.

The report also caters detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, it also incorporates potential opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Product:
CHO Media
HEK 293 Media
BHK Media
Vero Media
Stem Cell Media
Other Serum-free Media

By Application:
Biopharmaceutical Production
Monoclonal Antibodies
Vaccines Production
Tissue Engineering & Regenerative Medicine
Other Therapeutic Proteins
By Type:
Liquid Media
Semi-solid & Solid Media

By End-User:
Pharmaceutical & Biotechnology Companies
Research & Academic Institutes
Other End-Users

By Region:

North America


Asia Pacific
South Korea

Latin America

Middle East & Africa
Saudi Arabia
South Africa
Rest of Middle East & Africa

Chapter 1. Executive Summary
1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2030 (USD Billion)
1.2.1. Serum-free Media Market, by region, 2020-2030 (USD Billion)
1.2.2. Serum-free Media Market, by Product, 2020-2030 (USD Billion)
1.2.3. Serum-free Media Market, by Application, 2020-2030 (USD Billion)
1.2.4. Serum-free Media Market, by Type, 2020-2030 (USD Billion)
1.2.5. Serum-free Media Market, by End-User, 2020-2030 (USD Billion)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption
Chapter 2. Global Serum-free Media Market Definition and Scope
2.1. Objective of the Study
2.2. Market Definition & Scope
2.2.1. Industry Evolution
2.2.2. Scope of the Study
2.3. Years Considered for the Study
2.4. Currency Conversion Rates
Chapter 3. Global Serum-free Media Market Dynamics
3.1. Serum-free Media Market Impact Analysis (2020-2030)
3.1.1. Market Drivers Rising focus on cell-based therapeutics Growing production of new biopharmaceuticals Large Scale Manufacturing with cell culture
3.1.2. Market Challenges High Cost of Production Process
3.1.3. Market Opportunities Increasing funding in stem cell research Rising awareness of media-based testing of diagnostic
Chapter 4. Global Serum-free Media Market: Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.2. Porter’s 5 Force Impact Analysis
4.3. PEST Analysis
4.3.1. Political
4.3.2. Economic
4.3.3. Social
4.3.4. Technological
4.3.5. Environmental
4.3.6. Legal
4.4. Top investment opportunity
4.5. Top winning strategies
4.6. COVID-19 Impact Analysis
4.7. Disruptive Trends
4.8. Industry Expert Perspective
4.9. Analyst Recommendation & Conclusion
Chapter 5. Global Serum-free Media Market, by Product
5.1. Market Snapshot
5.2. Global Serum-free Media Market by Product, Performance – Potential Analysis
5.3. Global Serum-free Media Market Estimates & Forecasts by Product 2020-2030 (USD Billion)
5.4. Serum-free Media Market, Sub Segment Analysis
5.4.1. CHO Media
5.4.2. HEK 293 Media
5.4.3. BHK Media
5.4.4. Vero Medium
5.4.5. Stem Cell Medium
5.4.6. Other Serum-free Media
Chapter 6. Global Serum-free Media Market, by Application
6.1. Market Snapshot
6.2. Global Serum-free Media Market by Application, Performance – Potential Analysis
6.3. Global Serum-free Media Market Estimates & Forecasts by Application 2020-2030 (USD Billion)
6.4. Serum-free Media Market, Sub Segment Analysis
6.4.1. Biopharmaceutical Production
6.4.2. Monoclonal Antibodies
6.4.3. Vaccines Production
6.4.4. Tissue Engineering & Regenerative Medicine
6.4.5. Other Therapeutic Proteins
Chapter 7. Global Serum-free Media Market, by Type
7.1. Market Snapshot
7.2. Global Serum-free Media Market by Type, Performance – Potential Analysis
7.3. Global Serum-free Media Market Estimates & Forecasts by Type 2020-2030 (USD Billion)
7.4. Serum-free Media Market, Sub Segment Analysis
7.4.1. Liquid Media
7.4.2. Semi-solid & Solid Media
Chapter 8. Global Serum-free Media Market, by End-User
8.1. Market Snapshot
8.2. Global Serum-free Media Market by End-User, Performance – Potential Analysis
8.3. Global Serum-free Media Market Estimates & Forecasts by End-User 2020-2030 (USD Billion)
8.4. Serum-free Media Market, Sub Segment Analysis
8.4.1. Pharmaceutical & Biotechnology Companies
8.4.2. Research & Academic Institutes
8.4.3. Other End-Users
Chapter 9. Global Serum-free Media Market, Regional Analysis
9.1. Top Leading Countries
9.2. Top Emerging Countries
9.3. Serum-free Media Market, Regional Market Snapshot
9.4. North America Serum-free Media Market
9.4.1. U.S. Serum-free Media Market Product breakdown estimates & forecasts, 2020-2030 Application breakdown estimates & forecasts, 2020-2030 Type breakdown estimates & forecasts, 2020-2030 End-User breakdown estimates & forecasts, 2020-2030
9.4.2. Canada Serum-free Media Market
9.5. Europe Serum-free Media Market Snapshot
9.5.1. U.K. Serum-free Media Market
9.5.2. Germany Serum-free Media Market
9.5.3. France Serum-free Media Market
9.5.4. Spain Serum-free Media Market
9.5.5. Italy Serum-free Media Market
9.5.6. Rest of Europe Serum-free Media Market
9.6. Asia-Pacific Serum-free Media Market Snapshot
9.6.1. China Serum-free Media Market
9.6.2. India Serum-free Media Market
9.6.3. Japan Serum-free Media Market
9.6.4. Australia Serum-free Media Market
9.6.5. South Korea Serum-free Media Market
9.6.6. Rest of Asia Pacific Serum-free Media Market
9.7. Latin America Serum-free Media Market Snapshot
9.7.1. Brazil Serum-free Media Market
9.7.2. Mexico Serum-free Media Market
9.8. Middle East & Africa Serum-free Media Market
9.8.1. Saudi Arabia Serum-free Media Market
9.8.2. South Africa Serum-free Media Market
9.8.3. Rest of Middle East & Africa Serum-free Media Market

Chapter 10. Competitive Intelligence
10.1. Key Company SWOT Analysis
10.1.1. Company 1
10.1.2. Company 2
10.1.3. Company 3
10.2. Top Market Strategies
10.3. Company Profiles
10.3.1. Sartorius AG Key Information Overview Financial (Subject to Data Availability) Product Summary Recent Developments
10.3.2. FUJIFILM Holdings Corporation
10.3.3. Lonza Group AG
10.3.4. STEMCELL Technologies
10.3.5. PromoCell GmbH
10.3.6. Thermo Fisher Scientific Inc.
10.3.7. Corning Incorporated
10.3.8. FUJIFILM Irvine Scientific
10.3.9. Athena Environmental Sciences
10.3.10. Sartorius CellGenix
Chapter 11. Research Process
11.1. Research Process
11.1.1. Data Mining
11.1.2. Analysis
11.1.3. Market Estimation
11.1.4. Validation
11.1.5. Publishing
11.2. Research Attributes
11.3. Research Assumption

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To estimate and validate the market size, we employ both top-down and bottom-up approaches. The preference is given to a bottom-up approach, where key regional markets are analyzed as separate entities. This data is then integrated to obtain global estimates. This approach is crucial as it provides a deep understanding of the industry and helps minimize errors.
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Market driving trends and favorable economic conditions
Restraints and challenges that are expected to be encountered during the forecast period.
Anticipated opportunities for growth and development
Technological advancements and projected developments in the market
Consumer spending trends and dynamics
Shifts in consumer preferences and behaviors.
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Regulatory landscape and expected changes or developments.
The existing capacity in the market and any expected additions or expansions up to the end of the forecast period.
To assess the market impact of these parameters, we assign weights to each one and utilize weighted average analysis. This process allows us to quantify their influence on the market and derive an expected growth rate for the forecasted period. By considering these various factors and applying a weighted analysis approach, we strive to provide accurate and reliable market forecasts.
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