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Global Rare Hemophilia Factors Market to reach USD 502.58 million by the end of 2030

Global Rare Hemophilia Factors Market Size Study & Forecast, by Type (Factor I, Factor II, Factor V, Factor VII, Factor X, Factor XI, Factor XIII), by Treatment (Factor Concentrates, Fresh Frozen Plasma, Cryoprecipitate, Others) and Regional Analysis, 2023-2030

Product Code: HLSMDE-45623804
Publish Date: 15-11-2023
Page: 200

Global Rare Hemophilia Factors Market is valued at approximately USD 294.7 million in 2022 and is anticipated to grow with a healthy growth rate of more than 6.9% over the forecast period 2023-2030. Hemophilia is a genetic disorder that affects blood clotting, caused by a deficiency in clotting factors such as Factor VII, Factor IX, and Factor XIII. The market for rare hemophilia factors is growing due to advancements in early and accurate diagnosis, which helps healthcare providers identify patients with specific types of hemophilia and determine the best treatment options. Healthcare professionals and patients are becoming more aware of these advancements, and new treatment techniques that are being developed.

Also, the rising adoption and approval of new treatment techniques are driving the market. As per the article published by the National Institute of Health in 2021 under the title ‘Recent Advances in the Treatment of Hemophilia: A Review’, with the introduction of a bi-specific monoclonal antibody, a new era of prevention and treatment of bleeding started that clones the effects of Factors VIII in the tenase complex. The ongoing research to improve the efficacy and safety of rare hemophilia factor products is creating an opportunity for the market. The use of digital health technologies such as telemedicine and mobile health apps can be used to improve patients’ self-management. However, the high cost of treatments remains a significant challenge, especially in low-income countries. Also, the reimbursement policies have a significant impact on access to treatment.

The key regions considered for the Global Rare Hemophilic Factors Market study include Asia Pacific, North America, Europe, Latin America, and Middle East & Africa. North America dominated the market in 2022 due to the government’s initiatives to increase diagnosis rates and reduce treatment costs, research activities, and therapeutic advances in hemophilia. The National Organization for Rare Disorders (NORD) offers various research grants to study rare diseases. Furthermore, recent approvals by the U.S. FDA for some coagulation factor concentrates have assisted in boosting the regional market. Asia Pacific is expected to grow significantly over the forecast period, due to the rising incidence of autosomal recessive disorders in countries such as India, Pakistan, and China. According to a study titled “Epidemiological study of consanguineous marriage and its effects” published in the International Journal of Community Medicine and Public Health, the Middle East, Africa, and South Asia have a high prevalence of consanguineous marriages, estimated to be around 20.0% to 50.0% of all marriages.

Major market player included in this report are:
Novo Nordisk A/S
Biogen Inc.
Bayer Healthcare
Pfizer, Inc.
Shire Plc
Sanofi S.A
CSL Behring
Bio Products Laboratory Ltd.
Eli Lilly and Company

Recent Developments in the Market:
Ø In February 2022, Biocon acquired Viatris’ biosimilar portfolio, which resulted in strengthening its product offerings and revenue generation.
Ø In May 2022, F. Hoffmann-La Roche Ltd., a Swedish multinational healthcare company, extended its partnership with the World Federation of Hemophilia (WFH) until 2028 to provide access to hemophilia treatments. The company offer its prophylactic treatment for hemophilia A to the WFH’s Humanitarian Aid Program, that distribute it to people in areas with limited access to quality hemophilia treatments.
Ø In May 2022, Takeda Pharmaceutical Co Ltd launched Adynovate, an innovative extended half-life recombinant Factor VIII treatment in India for hemophilia A patients.
Ø In June 2022, the United States Food and Drug Administration granted breakthrough therapy designation to ‘efanesoctocog alfa’ for hemophilia A. This therapy is the first factor VIII therapy to be awarded Breakthrough Therapy designation by the FDA, based on data from the XTEND-1 Phase 3 study, which demonstrated clinically meaningful prevention of bleeds and superiority in the prevention of bleeding episodes compared to prior prophylaxis factor treatment.
Ø In August 2022, The Food and Drug Administration (FDA) announced the approval of Rebinyn, a coagulation factor IX recombinant, received approval for routine prophylaxis to reduce the frequency of bleeding episodes in children and adults with hemophilia B.

Global Rare Hemophilic Factors Market Report Scope:
ü Historical Data – 2020 – 2021
ü Base Year for Estimation – 2022
ü Forecast period – 2023-2030
ü Report Coverage – Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
ü Segments Covered – Type, Treatment, Region
ü Regional Scope – North America; Europe; Asia Pacific; Latin America; Middle East & Africa
ü Customization Scope – Free report customization (equivalent up to 8 analyst’s working hours) with purchase. Addition or alteration to country, regional & segment scope*

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.

The report also caters detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, it also incorporates potential opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and Type offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Type:
Factor I
Factor II
Factor V
Factor VII
Factor X
Factor XI
Factor XIII

By Treatment:
Factor Concentrates
Fresh Frozen Plasma

By Region:

North America


Asia Pacific
South Korea

Latin America

Middle East & Africa
Saudi Arabia
South Africa
Rest of Middle East & Africa

Chapter 1. Executive Summary
1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2030 (USD Million)
1.2.1. Rare Hemophilia Factors Market, by Region, 2020-2030 (USD Million)
1.2.2. Rare Hemophilia Factors Market, by Type, 2020-2030 (USD Million)
1.2.3. Rare Hemophilia Factors Market, by Treatment, 2020-2030 (USD Million)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption
Chapter 2. Global Rare Hemophilia Factors Market Definition and Scope
2.1. Objective of the Study
2.2. Market Definition & Scope
2.2.1. Industry Evolution
2.2.2. Scope of the Study
2.3. Years Considered for the Study
2.4. Currency Conversion Rates
Chapter 3. Global Rare Hemophilia Factors Market Dynamics
3.1. Rare Hemophilia Factors Market Impact Analysis (2020-2030)
3.1.1. Market Drivers Growing adoption and approval of new treatment techniques Increased awareness about rare hemophilia disease
3.1.2. Market Challenges High Cost of Rare Hemophilia treatments Inadequate reimbursement
3.1.3. Market Opportunities Ongoing research & development Use of digital health technologies
Chapter 4. Global Rare Hemophilia Factors Market Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.2. Porter’s 5 Force Impact Analysis
4.3. PEST Analysis
4.3.1. Political
4.3.2. Economical
4.3.3. Social
4.3.4. Technological
4.3.5. Environmental
4.3.6. Legal
4.4. Top investment opportunity
4.5. Top winning strategies
4.6. COVID-19 Impact Analysis
4.7. Disruptive Trends
4.8. Industry Expert Perspective
4.9. Analyst Recommendation & Conclusion
Chapter 5. Global Rare Hemophilia Factors Market, by Type
5.1. Market Snapshot
5.2. Global Rare Hemophilia Factors Market by Type, Performance – Potential Analysis
5.3. Global Rare Hemophilia Factors Market Estimates & Forecasts by Type 2020-2030 (USD Million)
5.4. Rare Hemophilia Factors Market, Sub-Segment Analysis
5.4.1. Factor I
5.4.2. Factor II
5.4.3. Factor V
5.4.4. Factor VII
5.4.5. Factor X
5.4.6. Factor XI
5.4.7. Factor XIII
Chapter 6. Global Rare Hemophilia Factors Market, by Treatment
6.1. Market Snapshot
6.2. Global Rare Hemophilia Factors Market by Treatment, Performance – Potential Analysis
6.3. Global Rare Hemophilia Factors Market Estimates & Forecasts by Treatment 2020-2030 (USD Million)
6.4. Rare Hemophilia Factors Market, Sub Segment Analysis
6.4.1. Factor Concentrates
6.4.2. Fresh Frozen Plasma
6.4.3. Cryoprecipitate
6.4.4. Others
Chapter 7. Global Rare Hemophilia Factors Market, Regional Analysis
7.1. Top Leading Countries
7.2. Top Emerging Countries
7.3. Rare Hemophilia Factors Market, Regional Market Snapshot
7.4. North America Rare Hemophilia Factors Market
7.4.1. U.S. Rare Hemophilia Factors Market Type breakdown estimates & forecasts, 2020-2030 Treatment breakdown estimates & forecasts, 2020-2030
7.4.2. Canada Rare Hemophilia Factors Market
7.5. Europe Rare Hemophilia Factors Market Snapshot
7.5.1. U.K. Rare Hemophilia Factors Market
7.5.2. Germany Rare Hemophilia Factors Market
7.5.3. France Rare Hemophilia Factors Market
7.5.4. Spain Rare Hemophilia Factors Market
7.5.5. Italy Rare Hemophilia Factors Market
7.5.6. Rest of Europe Rare Hemophilia Factors Market
7.6. Asia-Pacific Rare Hemophilia Factors Market Snapshot
7.6.1. China Rare Hemophilia Factors Market
7.6.2. India Rare Hemophilia Factors Market
7.6.3. Japan Rare Hemophilia Factors Market
7.6.4. Australia Rare Hemophilia Factors Market
7.6.5. South Korea Rare Hemophilia Factors Market
7.6.6. Rest of Asia Pacific Rare Hemophilia Factors Market
7.7. Latin America Rare Hemophilia Factors Market Snapshot
7.7.1. Brazil Rare Hemophilia Factors Market
7.7.2. Mexico Rare Hemophilia Factors Market
7.8. Middle East & Africa Rare Hemophilia Factors Market
7.8.1. Saudi Arabia Rare Hemophilia Factors Market
7.8.2. South Africa Rare Hemophilia Factors Market
7.8.3. Rest of Middle East & Africa Rare Hemophilia Factors Market

Chapter 8. Competitive Intelligence
8.1. Key Company SWOT Analysis
8.1.1. Company 1
8.1.2. Company 2
8.1.3. Company 3
8.2. Top Market Strategies
8.3. Company Profiles
8.3.1. Novo Nordisk A/S Key Information Overview Financial (Subject to Data Availability) Product Summary Recent Developments
8.3.2. Biogen Inc.
8.3.3. Bayer Healthcare
8.3.4. Pfizer, Inc.
8.3.5. Shire Plc
8.3.6. Sanofi S.A
8.3.7. CSL Behring
8.3.8. Bio Products Laboratory Ltd.
8.3.9. Eli Lilly and Company
8.3.10. GSK Plc
Chapter 9. Research Process
9.1. Research Process
9.1.1. Data Mining
9.1.2. Analysis
9.1.3. Market Estimation
9.1.4. Validation
9.1.5. Publishing
9.2. Research Attributes
9.3. Research Assumption

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Data Collection:
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To ensure the accuracy and reliability of our findings, we extensively leverage data science techniques, which help us minimize discrepancies and uncertainties in our analysis. We employ Data Science to clean and preprocess the data, ensuring its quality and reliability. This involves handling missing data, removing outliers, standardizing variables, and transforming data into suitable formats for analysis. The application of data science techniques enhances our accuracy, efficiency, and depth of analysis, enabling us to stay competitive in dynamic market environments.
Market Size Estimation:
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To estimate and validate the market size, we employ both top-down and bottom-up approaches. The preference is given to a bottom-up approach, where key regional markets are analyzed as separate entities. This data is then integrated to obtain global estimates. This approach is crucial as it provides a deep understanding of the industry and helps minimize errors.
In our forecasting process, we consider various parameters such as economic tools, technological analysis, industry experience, and domain expertise. By taking all these factors into account, we strive to produce accurate and reliable market forecasts. When forecasting, we take into consideration several parameters, which include:
Market driving trends and favorable economic conditions
Restraints and challenges that are expected to be encountered during the forecast period.
Anticipated opportunities for growth and development
Technological advancements and projected developments in the market
Consumer spending trends and dynamics
Shifts in consumer preferences and behaviors.
The current state of raw materials and trends in supply versus pricing
Regulatory landscape and expected changes or developments.
The existing capacity in the market and any expected additions or expansions up to the end of the forecast period.
To assess the market impact of these parameters, we assign weights to each one and utilize weighted average analysis. This process allows us to quantify their influence on the market and derive an expected growth rate for the forecasted period. By considering these various factors and applying a weighted analysis approach, we strive to provide accurate and reliable market forecasts.
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