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Global Oligonucleotide Synthesis Market to reach USD 16.67 billion by 2028.

Global Oligonucleotide Synthesis Market to reach USD 16.67 billion by 2028.

Product Code: HLSB-53989863
Publish Date: 27-03-2022
Page: 200

Global Oligonucleotide Synthesis Market is valued approximately USD 5.36 billion in 2021 and is anticipated to grow with a healthy growth rate of more than 17.6% over the forecast period 2022-2028.

Oligonucleotide synthesis is the chemical fusion of comparatively short fragments of nucleic acids with a defined chemical structure or sequence. The technique is majorly used in laboratory practice as it offers a fast and cost-effective way to contact custom-made oligonucleotides of the anticipated sequence. Moreover, it is also beneficial for performing molecular diagnosis in various diseases, involves detection of infectious diseases like SARS-COV2, hepatitis, and cancer diagnosis. The growing adoption of synthesized oligos in therapeutic applications, the with the growing focus on personalized medicin, coupled with the increasing number of government investments for synthetic biology and genome projects, are the major factors that may augment the market growth around the world. For instance, in August 2019, the Li Ka Shing Foundation (Hongkong) contributed USD 63 million for the introduction of the main institute for synthetic biology research at the Hong Kong University of Science and Technology (HKUST). The aim of this investment is to establish a new institute that will conduct research in synthetic biology for merging the processes and materials of biological systems & engineering. Moreover, in January 2020, in India, the Department of Biotechnology (DBT) introduced the “Genome India Project” (GIP) with the objective of accumulating10,000 genetic samples from citizens in India to create a reference genome. The major targeted areas of this project are rare genetic disorders, precision health, mutation spectrum of genetic & complex diseases that occur in the Indian population, translational research, and genetic epidemiology of multifactorial lifestyle diseases. However, complexities associated with therapeutic oligos impede the growth of the market over the forecast period of 2022-2028. Also, the growing presence of the leading market players in emerging economies is anticipated to act as a catalyzing factor for the market demand during the forecast period.

The key regions considered for the global Oligonucleotide Synthesis Market study include Asia Pacific, North America, Europe, Latin America, and the Rest of the World. North America is the leading region across the world in terms of market share owing to the growing demand for high-quality research tools for data reproducibility and the presence of leading market players in the region. Whereas, Asia-Pacific is anticipated to exhibit the highest CAGR over the forecast period 2022-2028. Factors such as increasing focus on improving the safety & quality of healthcare and developing personalized therapeutics, as well as increasing number of R&D activities in life sciences, would create lucrative growth prospects for the Oligonucleotide Synthesis Market across the Asia-Pacific region.

Major market players included in this report are:
Danaher Corporation
Thermo Fisher Scientific, Inc.
Merck KGaA
Maravai Life Sciences
Agilent Technologies, Inc.
Biogen Inc.
Sarepta Therapeutics, Inc.
LGC Biosearch Technologies
Bio-synthesis Inc.
TriLink BioTechnologies, LLC

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming eight years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within each of the regions and countries involved in the study. Furthermore, the report also caters the detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, the report shall also incorporate available opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:
By Product:
Oligonucleotide-based Drugs
Synthesized Oligonucleotides
By Application:
Research Applications
Other Research Applications
Diagnostic Applications
By Type:
Antisense Oligonucleotide-based Therapies
RNAi Oligonucleotide-based Therapies
CpG Oligonucleotide-based Therapies
By Disease Type:
Neurological Disorders
Infectious Diseases
Other Diseases
By End-Use:
Pharmaceutical & Biotechnology Companies
Diagnostic Laboratories
CROs and CMOs
Academic Research Institutes
By Region:
North America

Asia Pacific
South Korea
Latin America
Rest of the World

Furthermore, years considered for the study are as follows:

Historical year – 2018, 2019, 2020
Base year – 2021
Forecast period – 2022 to 2028

Target Audience of the Global Oligonucleotide Synthesis Market in Market Study:

Key Consulting Companies & Advisors
Large, medium-sized, and small enterprises
Venture capitalists
Value-Added Resellers (VARs)
Third-party knowledge providers
Investment bankers

Chapter 1. Executive Summary
1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2028 (USD Billion)
1.2.1. Global Oligonucleotide Synthesis Market, by Region, 2020-2028 (USD Billion)
1.2.2. Global Oligonucleotide Synthesis Market, by Product, 2020-2028 (USD Billion)
1.2.3. Global Oligonucleotide Synthesis Market, by Application, 2020-2028 (USD Billion)
1.2.4. Global Oligonucleotide Synthesis Market, by Type, 2020-2028 (USD Billion)
1.2.5. Global Oligonucleotide Synthesis Market, by Disease Type, 2020-2028 (USD Billion)
1.2.6. Global Oligonucleotide Synthesis Market, by End-Use, 2020-2028 (USD Billion)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption
Chapter 2. Global Oligonucleotide Synthesis Market Definition and Scope
2.1. Objective of the Study
2.2. Market Definition & Scope
2.2.1. Scope of the Study
2.2.2. Industry Evolution
2.3. Years Considered for the Study
2.4. Currency Conversion Rates
Chapter 3. Global Oligonucleotide Synthesis Market Dynamics
3.1. Oligonucleotide Synthesis Market Impact Analysis (2020-2028)
3.1.1. Market Drivers Growing use of synthesized oligos in therapeutic applications Increasing government investments for synthetic biology and genome projects
3.1.2. Market Challenges Complexities associated with therapeutic oligos
3.1.3. Market Opportunities Growing presence of the leading market players in emerging economies
Chapter 4. Global Oligonucleotide Synthesis Market Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.1.6. Futuristic Approach to Porter’s 5 Force Model (2019-2028)
4.2. PEST Analysis
4.2.1. Political
4.2.2. Economical
4.2.3. Social
4.2.4. Technological
4.3. Investment Adoption Model
4.4. Analyst Recommendation & Conclusion
4.5. Top investment opportunity
4.6. Top winning strategies
Chapter 5. Risk Assessment: COVID-19 Impact
5.1.1. Assessment of the overall impact of COVID-19 on the industry
5.1.2. Pre COVID-19 and post COVID-19 market scenario
Chapter 6. Global Oligonucleotide Synthesis Market, by Product
6.1. Market Snapshot
6.2. Global Oligonucleotide Synthesis Market by Product, Performance – Potential Analysis
6.3. Global Oligonucleotide Synthesis Market Estimates & Forecasts by Product 2019-2028 (USD Billion)
6.4. Oligonucleotide Synthesis Market, Sub Segment Analysis
6.4.1. Oligonucleotide-based Drugs
6.4.2. Synthesized Oligonucleotides
6.4.3. Reagents
6.4.4. Equipment
Chapter 7. Global Oligonucleotide Synthesis Market, by Application
7.1. Market Snapshot
7.2. Global Oligonucleotide Synthesis Market by Application, Performance – Potential Analysis
7.3. Global Oligonucleotide Synthesis Market Estimates & Forecasts by Application 2019-2028 (USD Billion)
7.4. Oligonucleotide Synthesis Market, Sub Segment Analysis
7.4.1. Research Applications PCR Sequencing Other Research Applications
7.4.2. Diagnostic Applications
Chapter 8. Global Oligonucleotide Synthesis Market, by Type
8.1. Market Snapshot
8.2. Global Oligonucleotide Synthesis Market by Type, Performance – Potential Analysis
8.3. Global Oligonucleotide Synthesis Market Estimates & Forecasts by Type 2019-2028 (USD Billion)
8.4. Oligonucleotide Synthesis Market, Sub Segment Analysis
8.4.1. Antisense Oligonucleotide-based Therapies
8.4.2. RNAi Oligonucleotide-based Therapies
8.4.3. CpG Oligonucleotide-based Therapies
Chapter 9. Global Oligonucleotide Synthesis Market, by Disease Type
9.1. Market Snapshot
9.2. Global Oligonucleotide Synthesis Market by Disease Type, Performance – Potential Analysis
9.3. Global Oligonucleotide Synthesis Market Estimates & Forecasts by Disease Type 2019-2028 (USD Billion)
9.4. Oligonucleotide Synthesis Market, Sub Segment Analysis
9.4.1. Neurological Disorders
9.4.2. Infectious Diseases
9.4.3. Other Diseases
Chapter 10. Global Oligonucleotide Synthesis Market, by End-Use
10.1. Market Snapshot
10.2. Global Oligonucleotide Synthesis Market by End-Use, Performance – Potential Analysis
10.3. Global Oligonucleotide Synthesis Market Estimates & Forecasts by End-Use 2019-2028 (USD Billion)
10.4. Oligonucleotide Synthesis Market, Sub Segment Analysis
10.4.1. Hospitals
10.4.2. Pharmaceutical & Biotechnology Companies
10.4.3. Diagnostic Laboratories
10.4.4. CROs and CMOs
10.4.5. Academic Research Institutes
Chapter 11. Global Oligonucleotide Synthesis Market, Regional Analysis
11.1. Oligonucleotide Synthesis Market, Regional Market Snapshot
11.2. North America Oligonucleotide Synthesis Market
11.2.1. U.S. Oligonucleotide Synthesis Market Product estimates & forecasts, 2019-2028 Application estimates & forecasts, 2019-2028 Type estimates & forecasts, 2019-2028 Disease Type estimates & forecasts, 2019-2028 End-Use estimates & forecasts, 2019-2028
11.2.2. Canada Oligonucleotide Synthesis Market
11.3. Europe Oligonucleotide Synthesis Market Snapshot
11.3.1. U.K. Oligonucleotide Synthesis Market
11.3.2. Germany Oligonucleotide Synthesis Market
11.3.3. France Oligonucleotide Synthesis Market
11.3.4. Spain Oligonucleotide Synthesis Market
11.3.5. Italy Oligonucleotide Synthesis Market
11.3.6. Rest of Europe Oligonucleotide Synthesis Market
11.4. Asia-Pacific Oligonucleotide Synthesis Market Snapshot
11.4.1. China Oligonucleotide Synthesis Market
11.4.2. India Oligonucleotide Synthesis Market
11.4.3. Japan Oligonucleotide Synthesis Market
11.4.4. Australia Oligonucleotide Synthesis Market
11.4.5. South Korea Oligonucleotide Synthesis Market
11.4.6. Rest of Asia Pacific Oligonucleotide Synthesis Market
11.5. Latin America Oligonucleotide Synthesis Market Snapshot
11.5.1. Brazil Oligonucleotide Synthesis Market
11.5.2. Mexico Oligonucleotide Synthesis Market
11.6. Rest of The World Oligonucleotide Synthesis Market
Chapter 12. Competitive Intelligence
12.1. Top Market Strategies
12.2. Company Profiles
12.2.1. Danaher Corporation Key Information Overview Financial (Subject to Data Availability) Product Summary Recent Developments
12.2.2. Thermo Fisher Scientific, Inc.
12.2.3. Merck KGaA
12.2.4. Maravai Life Sciences
12.2.5. Agilent Technologies, Inc.
12.2.6. Biogen Inc.
12.2.7. Sarepta Therapeutics, Inc.
12.2.8. LGC Biosearch Technologies
12.2.9. Bio-synthesis Inc.
12.2.10. TriLink BioTechnologies, LLC
Chapter 13. Research Process
13.1. Research Process
13.1.1. Data Mining
13.1.2. Analysis
13.1.3. Market Estimation
13.1.4. Validation
13.1.5. Publishing
13.2. Research Attributes
13.3. Research Assumption

At Bizwit Research and Consultancy, we employ a thorough and iterative research methodology with the goal of minimizing discrepancies, ensuring the provision of highly accurate estimates and predictions over the forecast period. Our approach involves a combination of bottom-up and top-down strategies to effectively segment and estimate quantitative aspects of the market, utilizing our proprietary data & AI tools. Our Proprietary Tools allow us for the creation of customized models specific to the research objectives. This enables us to develop tailored statistical models and forecasting algorithms to estimate market trends, future growth, or consumer behavior. The customization enhances the accuracy and relevance of the research findings.
We are dedicated to clearly communicating the purpose and objectives of each research project in the final deliverables. Our process begins by identifying the specific problem or challenge our client wishes to address, and from there, we establish precise research questions that need to be answered. To gain a comprehensive understanding of the subject matter and identify the most relevant trends and best practices, we conduct an extensive review of existing literature, industry reports, case studies, and pertinent academic research.
Critical elements of methodology employed for all our studies include:
Data Collection:
To determine the appropriate methods of data collection based on the research objectives, we consider both primary and secondary sources. Primary data collection involves gathering information directly from various industry experts in core and related fields, original equipment manufacturers (OEMs), vendors, suppliers, technology developers, alliances, and organizations. These sources encompass all segments of the value chain within the specific industry. Through in-depth interviews, we engage with key industry participants, subject-matter experts, C-level executives of major market players, industry consultants, and other relevant experts. This allows us to obtain and validate critical qualitative and quantitative information while evaluating market prospects. AI and Big Data are instrumental in our primary research, providing us with powerful tools to collect, analyze, and derive insights from data efficiently. These technologies contribute to the advancement of research methodologies, enabling us to make data-driven decisions and uncover valuable findings.
In addition to primary sources, we extensively utilize secondary sources to enhance our research. These include directories, databases, journals focusing on related industries, company newsletters, and information portals such as Bloomberg, D&B Hoovers, and Factiva. These secondary sources enable us to identify and gather valuable information for our comprehensive, technical, market-oriented, and commercial study of the market. Additionally, we utilize AI algorithms to automate the collection of vast amounts of data from various sources such as surveys, social media platforms, online transactions, and web scraping. And employ Big Data technologies for storage and processing of large datasets, ensuring that no valuable information is missed during the data collection process.
Data Analysis:
Our team of experts carefully examine the gathered data using suitable statistical techniques and qualitative analysis methods. For quantitative analysis, we employ descriptive statistics, regression analysis, and other advanced statistical methods, depending on the characteristics of the data. This analysis may also incorporate the utilization of AI tools and big data analysis techniques to extract meaningful insights.
To ensure the accuracy and reliability of our findings, we extensively leverage data science techniques, which help us minimize discrepancies and uncertainties in our analysis. We employ Data Science to clean and preprocess the data, ensuring its quality and reliability. This involves handling missing data, removing outliers, standardizing variables, and transforming data into suitable formats for analysis. The application of data science techniques enhances our accuracy, efficiency, and depth of analysis, enabling us to stay competitive in dynamic market environments.
Market Size Estimation:
Our proprietary data tools play a crucial role in deriving our market estimates and forecasts. Each study involves the creation of a unique and customized model. The model incorporates the gathered information on market dynamics, technology landscape, application development, and pricing trends. AI techniques, such as machine learning and deep learning, aid us to analyze patterns within the data to identify correlations, trends, and relationships. By recognizing patterns in consumer behavior, purchasing habits, or market dynamics, our AI algorithms aid us in more precise estimations of market size. These factors are simultaneously analyzed within the model, allowing for a comprehensive assessment. To quantify their impact over the forecast period, correlation, regression, and time series analysis are employed.
To estimate and validate the market size, we employ both top-down and bottom-up approaches. The preference is given to a bottom-up approach, where key regional markets are analyzed as separate entities. This data is then integrated to obtain global estimates. This approach is crucial as it provides a deep understanding of the industry and helps minimize errors.
In our forecasting process, we consider various parameters such as economic tools, technological analysis, industry experience, and domain expertise. By taking all these factors into account, we strive to produce accurate and reliable market forecasts. When forecasting, we take into consideration several parameters, which include:
Market driving trends and favorable economic conditions
Restraints and challenges that are expected to be encountered during the forecast period.
Anticipated opportunities for growth and development
Technological advancements and projected developments in the market
Consumer spending trends and dynamics
Shifts in consumer preferences and behaviors.
The current state of raw materials and trends in supply versus pricing
Regulatory landscape and expected changes or developments.
The existing capacity in the market and any expected additions or expansions up to the end of the forecast period.
To assess the market impact of these parameters, we assign weights to each one and utilize weighted average analysis. This process allows us to quantify their influence on the market and derive an expected growth rate for the forecasted period. By considering these various factors and applying a weighted analysis approach, we strive to provide accurate and reliable market forecasts.
Insight Generation & Report Presentation:
After conducting the research, our experts analyze the findings in relation to the research objectives and the specific needs of the client. They generate valuable insights and recommendations that directly address the client’s business challenges. These insights are carefully connected to the research findings to provide a comprehensive understanding.
Next, we create a well-structured research report that effectively communicates the research findings, insights, and recommendations to the client. To enhance clarity and comprehension, we utilize visual aids such as charts, graphs, and tables. These visual elements are employed to present the data in an engaging and easily understandable format, ensuring that the information is accessible and visually appealing to the client. Our aim is to deliver a clear and concise report that conveys the research findings effectively and provides actionable recommendations to meet the client’s specific needs.

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