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Global mRNA synthesis raw material market to reach USD 3242.7 million by the end of 2029.

Global mRNA Synthesis Raw Material Market Size study & Forecast, by Product (Capping agents, nucleotides, plasmid DNA, others) by Application (Therapeutics Production, Vaccine Production, Others), by End-user (Biopharmaceutical & Pharmaceutical Companies, CROs & CMOs, Academic & Research Institutions) and Regional Analysis, 2022-2029

Product Code: HLSB-23343010
Publish Date: 1-04-2023
Page: 200

Global mRNA synthesis raw material market is valued at approximately USD2746 million in 2021and and is anticipated to expand at a compound annual growth rate (CAGR) of 2.1% over the forecast period 2022-2029. Using a template consisting of the DNA nucleotide sequence, mRNA is created by the transcription process in the nucleus.mRNA’s adaptability and flexibility make it an excellent platform for developing therapeutic or preventive vaccines for a range of chronic and infectious diseases.The growing incidence of cancer and chronic disorders has raised the demand for gene treatments.

The market for mRNA synthesis and manufacturing services is expected to increase significantly over the next few years as a result of the rising demand for gene therapies, and the rise in chronic and infectious diseases. Funding is being provided for the creation of new mRNA therapies to numerous market participants and research institutions. For instance, the Canadian government provided USD 11.1 million in financing to the University of Columbia in October 2022 to further the development of mRNA vaccines. During the current Covid-2019 pandemic, many companies have chosen mRNA vaccine technology to combat coronavirus. Similarly, in December 2022, ExPLoRNA Therapeutics received USD 813,578 in funding from the Bill & Melinda Gates Foundation to further develop its mRNA technology. The emerging involvement of several market players is expected to drive the market further. The development of mRNA synthesis raw materials is hampered by a lack of adaptive, durable, and reasonably priced manufacturing procedures. The high cost of raw resources is the main impediment to progress.

The key regions considered for the Global mRNA synthesis raw material market study includes Asia Pacific, North America, Europe, Latin America, and Rest of the World. North America dominated the market for raw materials used in mRNA synthesis. The United States is forecasted to keep up its position as the industry leader because ofthe existence of sizable mRNA vaccine production facilities by renowned companies such asPfizer and Moderna. Due to this, this region will maintain its dominance throughout the forecast period. A significant percentage of the global market for mRNA synthesis raw materials was owned by Asia Pacific, which is anticipated to be the fastest-growing region due to rising R&D expenditures, a growth in the prevalence of infectious diseases, and a quick uptake of cutting-edge technology.
Major market player included in this report are:
Pfizer Inc.
Moderna, Inc.
BioNTech SE
Bayer AG
Boehringer Ingelheim
Sarepta Therapeutics
Alnylam Pharmaceuticals
Ionis Pharmaceuticals

Recent Developments in the Market:
 In November 2022, The BASE and Sartorius formed an alliance to facilitate the sharing of development methodologies and strategies for various nucleic acid-based products. The collaboration will enable the efficient application of cutting-edge methods and analytical thinking to design and plan techniques for nucleic acid products.
 Thermo Fisher Scientific unveiled a customised Dynabeads solution in October 2022, claiming that it aids in the synthesis and purification of mRNA for use in developing and manufacturing vaccines.
 A final deal was signed by Sanofi in August 2021 to buy all of the outstanding shares of Translate Bio, a company that develops therapies for messenger RNA (mRNA). The purchase is a component of Sanofi’s goal to hasten the application of mRNA technology in the creation of pharmaceuticals and vaccines.

Global mRNA synthesis raw material marketReport Scope:
Historical Data 2019-2020-2021
Base Year for Estimation 2021
Forecast period 2022-2029
Report Coverage Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
Segments Covered Type, application, end-user, region
Regional Scope North America; Europe; Asia Pacific; Latin America; Rest of the World
Customization Scope Free report customization (equivalent up to 8 analyst’s working hours) with purchase. Addition or alteration to country, regional & segment scope*

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.

The report also caters detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, it also incorporatespotential opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:
By Type:
Capping Agents
Plasmid DNA
By Application:
Therapeutics Production
Vaccine Production
By End-user:
Biopharmaceutical & Pharmaceutical Companies CROs & CMOs
Academic & Research Institutions
By Region:
North America
Asia Pacific
South Korea
Latin America
Rest of the World

Chapter 1. Executive Summary
1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2019-2029 (USD Million)
1.2.1. mRNA Synthesis Raw Material Market, by Region, 2019-2029 (USD Million)
1.2.2. mRNA Synthesis Raw Material Market, by Type,2019-2029 (USD Million)
1.2.3. mRNA synthesis raw material Market, by Application, 2019-2029 (USD Million)
1.2.4. mRNA synthesis raw material Market, by End-user, 2019-2029 (USD Million)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption
Chapter 2. Global mRNA Synthesis Raw Material Market Definition and Scope
2.1. Objective of the Study
2.2. Market Definition & Scope
2.2.1. Scope of the Study
2.2.2. Industry Evolution
2.3. Years Considered for the Study
2.4. Currency Conversion Rates
Chapter 3. Global mRNA Synthesis Raw Material Market Dynamics
3.1. mRNA Synthesis Raw Material Market Impact Analysis (2019-2029)
3.1.1. Market Drivers Increasing incidence of cancer and chronic disorders Active Involvement of big pharma players
3.1.2. Market Challenges High Cost of mRNA Synthesis Raw Material
3.1.3. Market Opportunities Necessity created by COVID-19 Considerable benefits of mRNA

Chapter 4. Global mRNA Synthesis Raw Material Market Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.2. Futuristic Approach to Porter’s 5 Force Model (2019-2029)
4.3. PEST Analysis
4.3.1. Political
4.3.2. Economical
4.3.3. Social
4.3.4. Technological
4.4. Investment Adoption Model
4.5. Analyst Recommendation & Conclusion
4.6. Top investment opportunity
4.7. Top winning strategies
Chapter 5. Risk Assessment: COVID-19 Impact
5.1. Assessment of the overall impact of COVID-19 on the industry
5.2. Pre COVID-19 and post COVID-19 Market scenario
Chapter 6. Global mRNA Synthesis Raw Material Market, by Type
6.1. Market Snapshot
6.2. Global mRNA Synthesis Raw Material Market by Type, Performance – Potential Analysis
6.3. Global mRNA Synthesis Raw Material Market Estimates & Forecasts by Type 2019-2029 (USD Million)
6.4. mRNA Synthesis Raw Material Market, Sub Segment Analysis
6.4.1. Capping Agents
6.4.2. Nucleotides
6.4.3. Plasmid DNA
6.4.4. Others
Chapter 7. Global mRNA synthesis raw material Market, by Application
7.1. Market Snapshot
7.2. Global mRNA synthesis raw material Market by Application, Performance – Potential Analysis
7.3. Global mRNA synthesis raw material Market Estimates & Forecasts by Application2019-2029 (USD Million)
7.4. mRNA synthesis raw material Market, Sub Segment Analysis
7.4.1. Therapeutics Production
7.4.2. Vaccine Production
7.4.3. Others
Chapter 8. Global mRNA synthesis raw material Market, by End-user
8.1. Market Snapshot
8.2. Global mRNA Synthesis Raw Material Market by End-user, Performance – Potential Analysis
8.3. Global mRNA synthesis raw material Market Estimates & Forecasts by End-user 2019-2029 (USD Million)
8.4. mRNA synthesis raw material Market, Sub Segment Analysis
8.4.1. Biopharmaceutical & Pharmaceutical Companies
8.4.2. CROs & CMOs
8.4.3. Academic & Research Institution
Chapter 9. Global mRNA Synthesis Raw Material Market, Regional Analysis
9.1. mRNA Synthesis Raw Material Market, Regional Market Snapshot
9.2. North America mRNA Synthesis Raw Material Market
9.2.1. U.S.mRNA Synthesis Raw Material Market Type breakdown estimates & forecasts, 2019-2029 Application breakdown estimates & forecasts, 2019-2029 End-user breakdown estimates & forecasts, 2019-2029
9.2.2. Canada mRNA Synthesis Raw Material Market
9.3. Europe mRNA Synthesis Raw Material Market Snapshot
9.3.1. U.K. mRNA Synthesis Raw Material Market
9.3.2. Germany mRNA Synthesis Raw Material Market
9.3.3. France mRNA Synthesis Raw Material Market
9.3.4. Spain mRNA Synthesis Raw Material Market
9.3.5. Italy mRNA Synthesis Raw Material Market
9.3.6. Rest of Europe mRNA Synthesis Raw Material Market
9.4. Asia-Pacific mRNA Synthesis Raw Material Market Snapshot
9.4.1. China mRNA Synthesis Raw Material Market
9.4.2. India mRNA Synthesis Raw Material Market
9.4.3. Japan mRNA Synthesis Raw Material Market
9.4.4. Australia mRNA Synthesis Raw Material Market
9.4.5. South Korea mRNA Synthesis Raw Material Market
9.4.6. Rest of Asia Pacific mRNA Synthesis Raw Material Market
9.5. Latin America mRNA Synthesis Raw Material Market Snapshot
9.5.1. Brazil mRNA Synthesis Raw Material Market
9.5.2. Mexico mRNA Synthesis Raw Material Market
9.6. Rest of The World mRNA Synthesis Raw Material Market

Chapter 10. Competitive Intelligence
10.1. Top Market Strategies
10.2. Company Profiles
10.2.1. Pfizer Inc. Key Information Overview Financial (Subject to Data Availability) Type Summary Recent Developments
10.2.2. Moderna, Inc.
10.2.3. BioNTech SE
10.2.4. Bayer AG
10.2.5. GlaxoSmithKline
10.2.6. Boehringer Ingelheim
10.2.7. CureVac
10.2.8. Sarepta Therapeutics
10.2.9. Alnylam Pharmaceuticals
10.2.10. Ionis Pharmaceuticals
Chapter 11. Research Process
11.1. Research Process
11.1.1. Data Mining
11.1.2. Analysis
11.1.3. Market Estimation
11.1.4. Validation
11.1.5. Publishing
11.2. Research Attributes
11.3. Research Assumption

At Bizwit Research and Consultancy, we employ a thorough and iterative research methodology with the goal of minimizing discrepancies, ensuring the provision of highly accurate estimates and predictions over the forecast period. Our approach involves a combination of bottom-up and top-down strategies to effectively segment and estimate quantitative aspects of the market, utilizing our proprietary data & AI tools. Our Proprietary Tools allow us for the creation of customized models specific to the research objectives. This enables us to develop tailored statistical models and forecasting algorithms to estimate market trends, future growth, or consumer behavior. The customization enhances the accuracy and relevance of the research findings.
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Data Collection:
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In addition to primary sources, we extensively utilize secondary sources to enhance our research. These include directories, databases, journals focusing on related industries, company newsletters, and information portals such as Bloomberg, D&B Hoovers, and Factiva. These secondary sources enable us to identify and gather valuable information for our comprehensive, technical, market-oriented, and commercial study of the market. Additionally, we utilize AI algorithms to automate the collection of vast amounts of data from various sources such as surveys, social media platforms, online transactions, and web scraping. And employ Big Data technologies for storage and processing of large datasets, ensuring that no valuable information is missed during the data collection process.
Data Analysis:
Our team of experts carefully examine the gathered data using suitable statistical techniques and qualitative analysis methods. For quantitative analysis, we employ descriptive statistics, regression analysis, and other advanced statistical methods, depending on the characteristics of the data. This analysis may also incorporate the utilization of AI tools and big data analysis techniques to extract meaningful insights.
To ensure the accuracy and reliability of our findings, we extensively leverage data science techniques, which help us minimize discrepancies and uncertainties in our analysis. We employ Data Science to clean and preprocess the data, ensuring its quality and reliability. This involves handling missing data, removing outliers, standardizing variables, and transforming data into suitable formats for analysis. The application of data science techniques enhances our accuracy, efficiency, and depth of analysis, enabling us to stay competitive in dynamic market environments.
Market Size Estimation:
Our proprietary data tools play a crucial role in deriving our market estimates and forecasts. Each study involves the creation of a unique and customized model. The model incorporates the gathered information on market dynamics, technology landscape, application development, and pricing trends. AI techniques, such as machine learning and deep learning, aid us to analyze patterns within the data to identify correlations, trends, and relationships. By recognizing patterns in consumer behavior, purchasing habits, or market dynamics, our AI algorithms aid us in more precise estimations of market size. These factors are simultaneously analyzed within the model, allowing for a comprehensive assessment. To quantify their impact over the forecast period, correlation, regression, and time series analysis are employed.
To estimate and validate the market size, we employ both top-down and bottom-up approaches. The preference is given to a bottom-up approach, where key regional markets are analyzed as separate entities. This data is then integrated to obtain global estimates. This approach is crucial as it provides a deep understanding of the industry and helps minimize errors.
In our forecasting process, we consider various parameters such as economic tools, technological analysis, industry experience, and domain expertise. By taking all these factors into account, we strive to produce accurate and reliable market forecasts. When forecasting, we take into consideration several parameters, which include:
Market driving trends and favorable economic conditions
Restraints and challenges that are expected to be encountered during the forecast period.
Anticipated opportunities for growth and development
Technological advancements and projected developments in the market
Consumer spending trends and dynamics
Shifts in consumer preferences and behaviors.
The current state of raw materials and trends in supply versus pricing
Regulatory landscape and expected changes or developments.
The existing capacity in the market and any expected additions or expansions up to the end of the forecast period.
To assess the market impact of these parameters, we assign weights to each one and utilize weighted average analysis. This process allows us to quantify their influence on the market and derive an expected growth rate for the forecasted period. By considering these various factors and applying a weighted analysis approach, we strive to provide accurate and reliable market forecasts.
Insight Generation & Report Presentation:
After conducting the research, our experts analyze the findings in relation to the research objectives and the specific needs of the client. They generate valuable insights and recommendations that directly address the client’s business challenges. These insights are carefully connected to the research findings to provide a comprehensive understanding.
Next, we create a well-structured research report that effectively communicates the research findings, insights, and recommendations to the client. To enhance clarity and comprehension, we utilize visual aids such as charts, graphs, and tables. These visual elements are employed to present the data in an engaging and easily understandable format, ensuring that the information is accessible and visually appealing to the client. Our aim is to deliver a clear and concise report that conveys the research findings effectively and provides actionable recommendations to meet the client’s specific needs.

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