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Global Ligases Enzyme Market to reach USD XX million by the end of 2030.

Global Ligases Enzyme Market Size study & Forecast, by Product (Quick Ligase, T4 DNA Ligase, E. Coli DNA Ligase, and others), by Source (Archaebacterium, Escherichia Coli, Thermus Thermophilus, Pyrococcus Furiosus), by Application (Molecular Cloning, Ligation Mediated PCR, Mutation Detection and others), by End User (Research Laboratories and Institutions, Pharmaceutical and Biopharmaceutical Companies, Diagnostic Laboratories) and Regional Analysis, 2023-2030

Product Code: HLSB-70702712
Publish Date: 20-12-2023
Page: 200

Global Ligases Enzyme Market is valued at approximately USD XX million in 2022 and is anticipated to grow with a healthy growth rate of more than 6.2% over the forecast period 2023-2030. Enzymes are biological catalysts that quicken chemical processes, particularly those that take place inside an organism’s body. Ligases are a particular class of enzymes that hasten the fusion of two big molecules, such as DNA. These enzymes are widely employed in gene synthesis, cloning, mutation detection, and next-generation sequencing. Enzymes for DNA ligases are also employed to address human dysfunctions and deficiencies. The market for ligases enzymes is expanding as a result of increased research efforts and R&D expenditures to create ligases as potential targets for cancer therapy. Additionally, as ligases are used in the identification of infectious illnesses and birth mutations, an increase in the prevalence of infectious diseases and birth genetic abnormalities is anticipated to fuel market expansion.

The increasing prevalence of various infectious diseases and genetic birth disorders due to its potential diagnostic and therapeutic properties. According to the WHO in 2022, an estimated 10.6 million tuberculosis cases were recorded globally in 2021. Thus, the rising frequency of TB drives the market for ligase enzymes by increasing the need for accurate and early diagnosis. Additionally, according to WHO statistics released in 2022, between January 24 and February 6, 2022, about 12,368 persons tested positive for influenza viruses, with 8,423 (68.1%) falling under the influenza A category and 3,945 (31.9%) falling under the influenza B category. There were 171 (6.4%) influenza A(H1N1) pdm09 subtypes (H3N2) and roughly 2,483 (93.6%) influenza A viruses overall. Such widespread outbreaks of infectious illnesses are predicted to increase demand for ligase enzymes and boost market expansion. Similar to this, the development of ligases as cancer therapeutic treatments is also anticipated to be one of the major market-driving drivers. Additionally, the presence of many vendors that offer ligase enzymes provides lucrative opportunities. However, the risk of the high sensitivity of the ligase enzyme stifles market growth throughout the forecast period of 2023-2030.

The key regions considered for the Global Ligases Enzyme Market study includes Asia Pacific, North America, Europe, Latin America, and Middle East & Africa. North America dominated the market in 2022 owing to well-established end-user sectors such as molecular biology laboratories, research institutions, and pharmaceutical corporations. For instance, according to CDC statistics in March 2022, TB incidence in the United States grew by 9.4% from 2020 to 2021. In addition, the VDH article published in 2022 said that the incidence rate of TB in Mexico was approximately 20 per 100,000 people per year. Furthermore, the Tand F Journal study released in March 2022 said that the yearly incidence rate of TB among the Canadian population was 4.7 per 100,000 people. Such increasing infectious illness rates are likely to fuel demand for ligase enzymes, adding to market expansion over the forecast period. Anticipated substantial growth in the Asia Pacific region during the forecast period is attributed to noteworthy advancements in technological integration and rapid healthcare development in Japan and China. The presence of robust clinical development frameworks, coupled with increasing research and development activities in emerging economies like Australia and India, presents significant opportunities. This scenario is expected to contribute to the overall market growth in the Asia Pacific region throughout the forecast period.

Major market player included in this report are:
Agilent Technologies Inc.
Arctic Zymes Technologies ASA
Bio-Rad Laboratories Inc.
Codexis Inc.
F. Hoffmann-La Roche Ltd.
Inspiralis Limited
The Merck Group
New England Biolabs (UK) Ltd.
Promega Corporation

Recent Developments in the Market:
Ø In June 2022, Nurix Therapeutics Launches Expansion Cohort Evaluating NX-2127 in CLL. Nurix Therapeutics has started an ongoing phase 1 study (NCT04830137) to investigate the immunomodulatory oral BTK inhibitor NX-2127. Patients with chronic lymphocytic leukaemia (CLL) expected to be the focus of this trial, the first of three phase 1b expansion cohorts investigating NX-2121.
Ø In June 2022, QIAGEN N.V. has disclosed its agreements to secure a 96% majority ownership stake in BLIRT SA (Polish Stock Exchange: BLR), a Gdansk, Poland-based manufacturer specializing in recombinant enzymes for the life science industry. This strategic acquisition of BLIRT by QIAGEN introduces synergistic capabilities, enhancing growth prospects for the enzymes and reagents business.
Global Ligases Enzyme Market Report Scope:
ü Historical Data – 2020 – 2021
ü Base Year for Estimation – 2022
ü Forecast period – 2023-2030
ü Report Coverage – Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
ü Segments Covered – Product, Source, Application, End User, Region
ü Regional Scope – North America; Europe; Asia Pacific; Latin America; Middle East & Africa
ü Customization Scope – Free report customization (equivalent up to 8 analyst’s working hours) with purchase. Addition or alteration to country, regional & segment scope*

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.

The report also caters detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, it also incorporates potential opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Product:
Quick Ligase
T4 DNA Ligase
E. Coli DNA Ligase
By Source:
Escherichia Coli
Thermus Thermophilus
Pyrococcus Furiosus
By Application:
Molecular Cloning
Ligation Mediated PCR
Mutation Detection
By End User:
Research Laboratories and Institutions
Pharmaceutical and Biopharmaceutical Companies
Diagnostic Laboratories
By Region:

North America


Asia Pacific
South Korea

Latin America

Middle East & Africa
Saudi Arabia
South Africa
Rest of Middle East & Africa

Chapter 1. Executive Summary
1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2030 (USD Million)
1.2.1. Ligases Enzyme Market, by Region, 2020-2030 (USD Million)
1.2.2. Ligases Enzyme Market, by Product, 2020-2030 (USD Million)
1.2.3. Ligases Enzyme Market, by Source, 2020-2030 (USD Million)
1.2.4. Ligases Enzyme Market, by Application, 2020-2030 (USD Million)
1.2.5. Ligases Enzyme Market, by End User, 2020-2030 (USD Million)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption
Chapter 2. Global Ligases Enzyme Market Definition and Scope
2.1. Objective of the Study
2.2. Market Definition & Scope
2.2.1. Industry Evolution
2.2.2. Scope of the Study
2.3. Years Considered for the Study
2.4. Currency Conversion Rates
Chapter 3. Global Ligases Enzyme Market Dynamics
3.1. Ligases Enzyme Market Impact Analysis (2020-2030)
3.1.1. Market Drivers Increase in Prevalence of Birth Genetic Disorders and Infectious Diseases Rising Research Activities for Sequencing Applications
3.1.2. Market Challenges Risk of High Sensitivity of the Enzyme
3.1.3. Market Opportunities Increasing involvement of enzymes in protein engineering
Chapter 4. Global Ligases Enzyme Market Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.2. Porter’s 5 Force Impact Analysis
4.3. PEST Analysis
4.3.1. Political
4.3.2. Economical
4.3.3. Social
4.3.4. Technological
4.3.5. Environmental
4.3.6. Legal
4.4. Top investment opportunity
4.5. Top winning strategies
4.6. COVID-19 Impact Analysis
4.7. Disruptive Trends
4.8. Industry Expert Perspective
4.9. Analyst Recommendation & Conclusion
Chapter 5. Global Ligases Enzyme Market, by Product
5.1. Market Snapshot
5.2. Global Ligases Enzyme Market by Product, Performance – Potential Analysis
5.3. Global Ligases Enzyme Market Estimates & Forecasts by Product 2020-2030 (USD Million)
5.4. Ligases Enzyme Market, Sub Segment Analysis
5.4.1. Quick Ligase
5.4.2. T4 DNA Ligase
5.4.3. E. Coli DNA Ligase
5.4.4. others
Chapter 6. Global Ligases Enzyme Market, by Source
6.1. Market Snapshot
6.2. Global Ligases Enzyme Market by Source, Performance – Potential Analysis
6.3. Global Ligases Enzyme Market Estimates & Forecasts by Source 2020-2030 (USD Million)
6.4. Ligases Enzyme Market, Sub Segment Analysis
6.4.1. Archaebacterium
6.4.2. Escherichia Coli
6.4.3. Thermus Thermophilus
6.4.4. Pyro coccus Furiosus
Chapter 7. Global Ligases Enzyme Market, by Application
7.1. Market Snapshot
7.2. Global Ligases Enzyme Market by Application, Performance – Potential Analysis
7.3. Global Ligases Enzyme Market Estimates & Forecasts by Application 2020-2030 (USD Million)
7.4. Ligases Enzyme Market, Sub Segment Analysis
7.4.1. Molecular Cloning
7.4.2. Ligation Mediated PCR
7.4.3. Mutation Detection
7.4.4. others
Chapter 8. Global Ligases Enzyme Market, by End User
8.1. Market Snapshot
8.2. Global Ligases Enzyme Market by End User, Performance – Potential Analysis
8.3. Global Ligases Enzyme Market Estimates & Forecasts by End User 2020-2030 (USD Million)
8.4. Ligases Enzyme Market, Sub Segment Analysis
8.4.1. Research Laboratories and Institutions
8.4.2. Pharmaceutical and Biopharmaceutical Companies
8.4.3. Diagnostic Laboratories
Chapter 9. Global Ligases Enzyme Market, Regional Analysis
9.1. Top Leading Countries
9.2. Top Emerging Countries
9.3. Ligases Enzyme Market, Regional Market Snapshot
9.4. North America Ligases Enzyme Market
9.4.1. U.S. Ligases Enzyme Market Product breakdown estimates & forecasts, 2020-2030 Source breakdown estimates & forecasts, 2020-2030 Application breakdown estimates & forecasts, 2020-2030 End User breakdown estimates & forecasts, 2020-2030
9.4.2. Canada Ligases Enzyme Market
9.5. Europe Ligases Enzyme Market Snapshot
9.5.1. U.K. Ligases Enzyme Market
9.5.2. Germany Ligases Enzyme Market
9.5.3. France Ligases Enzyme Market
9.5.4. Spain Ligases Enzyme Market
9.5.5. Italy Ligases Enzyme Market
9.5.6. Rest of Europe Ligases Enzyme Market
9.6. Asia-Pacific Ligases Enzyme Market Snapshot
9.6.1. China Ligases Enzyme Market
9.6.2. India Ligases Enzyme Market
9.6.3. Japan Ligases Enzyme Market
9.6.4. Australia Ligases Enzyme Market
9.6.5. South Korea Ligases Enzyme Market
9.6.6. Rest of Asia Pacific Ligases Enzyme Market
9.7. Latin America Ligases Enzyme Market Snapshot
9.7.1. Brazil Ligases Enzyme Market
9.7.2. Mexico Ligases Enzyme Market
9.8. Middle East & Africa Ligases Enzyme Market
9.8.1. Saudi Arabia Ligases Enzyme Market
9.8.2. South Africa Ligases Enzyme Market
9.8.3. Rest of Middle East & Africa Ligases Enzyme Market

Chapter 10. Competitive Intelligence
10.1. Key Company SWOT Analysis
10.1.1. Company 1
10.1.2. Company 2
10.1.3. Company 3
10.2. Top Market Strategies
10.3. Company Profiles
10.3.1. Agilent Technologies Inc. Key Information Overview Financial (Subject to Data Availability) Product Summary Recent Developments
10.3.2. Arctic Zymes Technologies ASA
10.3.3. Bio-Rad Laboratories Inc.
10.3.4. BLIRT S.A.
10.3.5. Codexis Inc.
10.3.6. F. Hoffmann-La Roche Ltd.
10.3.7. Inspiralis Limited
10.3.8. The Merck Group
10.3.9. New England Biolabs (UK) Ltd.
10.3.10. Promega Corporation
Chapter 11. Research Process
11.1. Research Process
11.1.1. Data Mining
11.1.2. Analysis
11.1.3. Market Estimation
11.1.4. Validation
11.1.5. Publishing
11.2. Research Attributes
11.3. Research Assumption

At Bizwit Research and Consultancy, we employ a thorough and iterative research methodology with the goal of minimizing discrepancies, ensuring the provision of highly accurate estimates and predictions over the forecast period. Our approach involves a combination of bottom-up and top-down strategies to effectively segment and estimate quantitative aspects of the market, utilizing our proprietary data & AI tools. Our Proprietary Tools allow us for the creation of customized models specific to the research objectives. This enables us to develop tailored statistical models and forecasting algorithms to estimate market trends, future growth, or consumer behavior. The customization enhances the accuracy and relevance of the research findings.
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Data Collection:
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Our team of experts carefully examine the gathered data using suitable statistical techniques and qualitative analysis methods. For quantitative analysis, we employ descriptive statistics, regression analysis, and other advanced statistical methods, depending on the characteristics of the data. This analysis may also incorporate the utilization of AI tools and big data analysis techniques to extract meaningful insights.
To ensure the accuracy and reliability of our findings, we extensively leverage data science techniques, which help us minimize discrepancies and uncertainties in our analysis. We employ Data Science to clean and preprocess the data, ensuring its quality and reliability. This involves handling missing data, removing outliers, standardizing variables, and transforming data into suitable formats for analysis. The application of data science techniques enhances our accuracy, efficiency, and depth of analysis, enabling us to stay competitive in dynamic market environments.
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Our proprietary data tools play a crucial role in deriving our market estimates and forecasts. Each study involves the creation of a unique and customized model. The model incorporates the gathered information on market dynamics, technology landscape, application development, and pricing trends. AI techniques, such as machine learning and deep learning, aid us to analyze patterns within the data to identify correlations, trends, and relationships. By recognizing patterns in consumer behavior, purchasing habits, or market dynamics, our AI algorithms aid us in more precise estimations of market size. These factors are simultaneously analyzed within the model, allowing for a comprehensive assessment. To quantify their impact over the forecast period, correlation, regression, and time series analysis are employed.
To estimate and validate the market size, we employ both top-down and bottom-up approaches. The preference is given to a bottom-up approach, where key regional markets are analyzed as separate entities. This data is then integrated to obtain global estimates. This approach is crucial as it provides a deep understanding of the industry and helps minimize errors.
In our forecasting process, we consider various parameters such as economic tools, technological analysis, industry experience, and domain expertise. By taking all these factors into account, we strive to produce accurate and reliable market forecasts. When forecasting, we take into consideration several parameters, which include:
Market driving trends and favorable economic conditions
Restraints and challenges that are expected to be encountered during the forecast period.
Anticipated opportunities for growth and development
Technological advancements and projected developments in the market
Consumer spending trends and dynamics
Shifts in consumer preferences and behaviors.
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To assess the market impact of these parameters, we assign weights to each one and utilize weighted average analysis. This process allows us to quantify their influence on the market and derive an expected growth rate for the forecasted period. By considering these various factors and applying a weighted analysis approach, we strive to provide accurate and reliable market forecasts.
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