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Global In Vivo CRO Market to reach USD 6.77 billion by 2028.

Global In Vivo CRO Market Size study, by Type (Rodent, Non-Rodent), By GLP Type (Non-GLP, GLP Toxicology), By Indication (Autoimmune/Inflammation Conditions, Pain Management, Oncology, CNS Conditions, Diabetes, Obesity, Others) and Regional Forecasts 2022-2028.

Product Code: HLSHS-70884766
Publish Date: 5-07-2022
Page: 200

Global In Vivo CRO Market is valued approximately USD 3.9 billion in 2021 and is anticipated to grow with a healthy growth rate of more than 8.20% over the forecast period 2022-2028. Contract research organizations (CROs) that conduct biopharmaceutical research in vivo are known as in-vivo contract research organizations (CROs). With the increased popularity of biologics over small molecule medications, in-vivo CROs are gaining appeal. Rising demand for sophisticated pharmaceuticals, CROs implementing worldwide standards, and big pharmaceutical firms outsourcing R&D efforts to focus more on their core capabilities are driving market expansion. Furthermore, outsourcing is less expensive than performing an in-house study. This is anticipated to increase demand for in vivo CROs. The demand for a significant number of animal models has quickly expanded across the world in order to ensure the safety and efficacy of novel entities prior to human trials. As a result, the use of these animal models in research centres, which closely resemble the clinical manifestation of SARS-CoV-2, has bolstered market growth. The most prevalent cause of insulin resistance is obesity. According to a National Center for Biotechnology Information (NCBI) research published in 2019, roughly 39% of individuals globally are obese or overweight and at risk of acquiring Type 2 Diabetes Mellitus (T2DM). T2DM is characterized by a gradual reduction in beta-cell activity and insulin resistance. The epidemic has created extraordinary interruption in research and clinical studies over the previous two years. The COVID-19 pandemic was claimed to have interrupted 1,079 clinical studies financed by sponsors, partners, or CROs in November 2021. As of June 2021, oncology was the most affected therapeutic area, accounting for approximately a quarter of all interrupted studies. Clinical trial interruptions would have an influence on the in vivo studies industry. However, sponsors raised CRO outsourced trial spending in 2021 compared to the previous year, according to a recent Outsourcing-Pharma study. The majority of investments are going toward enhancing CRO assistance, particularly technology-based solutions to increase patient access and engagement. Furthermore, a rise in M&A activity by big and mid-sized CROs in 2021 would have a significant post-COVID-19 influence on market growth. Sygnature Discovery, for example, was sold to Rothschild’s private equity arm, Five Arrows Principal Investment, and later to Keensight. This illustrates the enthusiasm of investors to invest in early-stage R&D CROs. Furthermore, a rise in M&A activity by big and mid-sized CROs in 2021 would have a significant post-COVID-19 influence on market growth. However, pharmaceutical companies’ shifting preference for outsourcing clinical and preclinical trials impedes the growth of the market over the forecast period of 2022-2028.

The key regions considered for the Global In Vivo CRO Market study includes Asia Pacific, North America, Europe, Latin America, and Rest of the World. North America emerged as the market leader. The existence of significant financing in this region influenced research efforts positively. For example, the United States has the largest per capita healthcare spending and funding from government agencies such as the National Institutes of Health (NIH), which promotes research. Over the projection period, Asia Pacific is expected to have the quickest CAGR. The region has a sizable treatment-naive population. It accounts for 53% of the world’s urban population and has three times the yearly rate of urbanization as the West. These reasons are driving increase in clinical trials in Asia Pacific.

Major market player included in this report are:
Covance, Inc.
Theorem Clinical Research
WuXi AppTec, Inc.
inVentiv Health
Evotec (US), Inc.
Charles River Laboratories
American Preclinical Services, LLC.
GVK Biosciences Private Limited
Iris Pharma
Pronexus Analytical AB
The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming eight years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within each of the regions and countries involved in the study. Furthermore, the report also caters the detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, the report shall also incorporate available opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:
By Type:
Rodent
Non-Rodent
By GLP Type:
Non-GLP
GLP Toxicology
By Indication:
Autoimmune/Inflammation Conditions
Pain Management
Oncology
CNS Conditions
Diabetes
Obesity
Others
By Region:
North America
U.S.
Canada
Europe
UK
Germany
France
Spain
Italy
ROE

Asia Pacific
China
India
Japan
Australia
South Korea
RoAPAC
Latin America
Brazil
Mexico
Rest of the World

Furthermore, years considered for the study are as follows:

Historical year – 2018, 2019, 2020
Base year – 2021
Forecast period – 2022 to 2028

Target Audience of the Global In Vivo CRO Market in Market Study:

Key Consulting Companies & Advisors
Large, medium-sized, and small enterprises
Venture capitalists
Value-Added Resellers (VARs)
Third-party knowledge providers
Investment bankers
Investors

Chapter 1. Executive Summary
1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2028 (USD Billion)
1.2.1. In Vivo CRO Market, by Region, 2020-2028 (USD Billion)
1.2.2. In Vivo CRO Market, by Type, 2020-2028 (USD Billion)
1.2.3. In Vivo CRO Market, by GLP Type, 2020-2028 (USD Billion)
1.2.4. In Vivo CRO Market, by Indication, 2020-2028 (USD Billion)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption
Chapter 2. Global In Vivo CRO Market Definition and Scope
2.1. Objective of the Study
2.2. Market Definition & Scope
2.2.1. Scope of the Study
2.2.2. Industry Evolution
2.3. Years Considered for the Study
2.4. Currency Conversion Rates
Chapter 3. Global In Vivo CRO Market Dynamics
3.1. In Vivo CRO Market Impact Analysis (2020-2028)
3.1.1. Market Drivers
3.1.1.1. Implementation of international standards by CROs
3.1.1.2. Rise in outsourcing of R&D activities by major pharmaceutical companies
3.1.2. Market Challenges
3.1.2.1. pharmaceutical companies’ shifting preference for outsourcing clinical and preclinical trials
3.1.3. Market Opportunities
3.1.3.1. Technological improvements in In Vivo CRO
Chapter 4. Global In Vivo CRO Market Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.1.6. Futuristic Approach to Porter’s 5 Force Model (2018-2028)
4.2. PEST Analysis
4.2.1. Political
4.2.2. Economical
4.2.3. Social
4.2.4. Technological
4.3. Investment Adoption Model
4.4. Analyst Recommendation & Conclusion
4.5. Top investment opportunity
4.6. Top winning strategies
Chapter 5. Risk Assessment: COVID-19 Impact
5.1.1. Assessment of the overall impact of COVID-19 on the industry
5.1.2. Pre COVID-19 and post COVID-19 Market scenario
Chapter 6. Global In Vivo CRO Market, by Type
6.1. Market Snapshot
6.2. Global In Vivo CRO Market by Type, Performance – Potential Analysis
6.3. Global In Vivo CRO Market Estimates & Forecasts by Type 2018-2028 (USD Billion)
6.4. In Vivo CRO Market, Sub Segment Analysis
6.4.1. Rodent
6.4.2. Non-Rodent
Chapter 7. Global In Vivo CRO Market, by GLP Type
7.1. Market Snapshot
7.2. Global In Vivo CRO Market by GLP Type, Performance – Potential Analysis
7.3. Global In Vivo CRO Market Estimates & Forecasts by GLP Type 2018-2028 (USD Billion)
7.4. In Vivo CRO Market, Sub Segment Analysis
7.4.1. Non-GLP
7.4.2. GLP Toxicology
Chapter 8. Global In Vivo CRO Market, by Indication
8.1. Market Snapshot
8.2. Global In Vivo CRO Market by Indication, Performance – Potential Analysis
8.3. Global In Vivo CRO Market Estimates & Forecasts by Indication 2018-2028 (USD Billion)
8.4. In Vivo CRO Market, Sub Segment Analysis
8.4.1. Autoimmune/Inflammation Conditions
8.4.2. Pain Management
8.4.3. Oncology
8.4.4. CNS Conditions
8.4.5. Diabetes
8.4.6. Obesity
8.4.7. Others
Chapter 9. Global In Vivo CRO Market, Regional Analysis
9.1. In Vivo CRO Market, Regional Market Snapshot
9.2. North America In Vivo CRO Market
9.2.1. U.S. In Vivo CRO Market
9.2.1.1. Type breakdown estimates & forecasts, 2018-2028
9.2.1.2. GLP Type breakdown estimates & forecasts, 2018-2028
9.2.1.3. Indication breakdown estimates & forecasts, 2018-2028
9.2.2. Canada In Vivo CRO Market
9.3. Europe In Vivo CRO Market Snapshot
9.3.1. U.K. In Vivo CRO Market
9.3.2. Germany In Vivo CRO Market
9.3.3. France In Vivo CRO Market
9.3.4. Spain In Vivo CRO Market
9.3.5. Italy In Vivo CRO Market
9.3.6. Rest of Europe In Vivo CRO Market
9.4. Asia-Pacific In Vivo CRO Market Snapshot
9.4.1. China In Vivo CRO Market
9.4.2. India In Vivo CRO Market
9.4.3. Japan In Vivo CRO Market
9.4.4. Australia In Vivo CRO Market
9.4.5. South Korea In Vivo CRO Market
9.4.6. Rest of Asia Pacific In Vivo CRO Market
9.5. Latin America In Vivo CRO Market Snapshot
9.5.1. Brazil In Vivo CRO Market
9.5.2. Mexico In Vivo CRO Market
9.6. Rest of The World In Vivo CRO Market

Chapter 10. Competitive Intelligence
10.1. Top Market Strategies
10.2. Company Profiles
10.2.1. Covance, Inc.
10.2.1.1. Key Information
10.2.1.2. Overview
10.2.1.3. Financial (Subject to Data Availability)
10.2.1.4. Type Summary
10.2.1.5. Recent Developments
10.2.2. Theorem Clinical Research
10.2.3. WuXi AppTec, Inc.
10.2.4. inVentiv Health
10.2.5. Evotec (US), Inc.
10.2.6. Charles River Laboratories
10.2.7. American Preclinical Services, LLC.
10.2.8. GVK Biosciences Private Limited
10.2.9. Iris Pharma
10.2.10. Pronexus Analytical ABss
Chapter 11. Research Process
11.1. Research Process
11.1.1. Data Mining
11.1.2. Analysis
11.1.3. Market Estimation
11.1.4. Validation
11.1.5. Publishing
11.2. Research Attributes
11.3. Research Assumption

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Critical elements of methodology employed for all our studies include:
Data Collection:
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Data Analysis:
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To ensure the accuracy and reliability of our findings, we extensively leverage data science techniques, which help us minimize discrepancies and uncertainties in our analysis. We employ Data Science to clean and preprocess the data, ensuring its quality and reliability. This involves handling missing data, removing outliers, standardizing variables, and transforming data into suitable formats for analysis. The application of data science techniques enhances our accuracy, efficiency, and depth of analysis, enabling us to stay competitive in dynamic market environments.
Market Size Estimation:
Our proprietary data tools play a crucial role in deriving our market estimates and forecasts. Each study involves the creation of a unique and customized model. The model incorporates the gathered information on market dynamics, technology landscape, application development, and pricing trends. AI techniques, such as machine learning and deep learning, aid us to analyze patterns within the data to identify correlations, trends, and relationships. By recognizing patterns in consumer behavior, purchasing habits, or market dynamics, our AI algorithms aid us in more precise estimations of market size. These factors are simultaneously analyzed within the model, allowing for a comprehensive assessment. To quantify their impact over the forecast period, correlation, regression, and time series analysis are employed.
To estimate and validate the market size, we employ both top-down and bottom-up approaches. The preference is given to a bottom-up approach, where key regional markets are analyzed as separate entities. This data is then integrated to obtain global estimates. This approach is crucial as it provides a deep understanding of the industry and helps minimize errors.
In our forecasting process, we consider various parameters such as economic tools, technological analysis, industry experience, and domain expertise. By taking all these factors into account, we strive to produce accurate and reliable market forecasts. When forecasting, we take into consideration several parameters, which include:
Market driving trends and favorable economic conditions
Restraints and challenges that are expected to be encountered during the forecast period.
Anticipated opportunities for growth and development
Technological advancements and projected developments in the market
Consumer spending trends and dynamics
Shifts in consumer preferences and behaviors.
The current state of raw materials and trends in supply versus pricing
Regulatory landscape and expected changes or developments.
The existing capacity in the market and any expected additions or expansions up to the end of the forecast period.
To assess the market impact of these parameters, we assign weights to each one and utilize weighted average analysis. This process allows us to quantify their influence on the market and derive an expected growth rate for the forecasted period. By considering these various factors and applying a weighted analysis approach, we strive to provide accurate and reliable market forecasts.
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