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Global CAR T-Cell therapy Market to reach USD 5.31 billion by the end of 2030.

Global CAR T-Cell therapy Market Size study & Forecast, by Indication (Lymphoma, Acute Lymphocytic Leukemia, Others), By Drug Type (Axicabtagene Ciloleucel, Tisagenlecleucel, Brexucabtagene Autoleucel, Others), By End user (Hospitals, Cancer Treatment Centers), and Regional Analysis, 2023-2030

Product Code: HLSDT-22974664
Publish Date: 20-05-2023
Page: 200

Global CAR T-Cell therapy Market is valued at approximately USD 1.93 billion in 2022 and is anticipated to grow with a healthy growth rate of more than 13.5% over the forecast period 2023-2030. Chimeric antigen receptor (CAR) T cell therapy is a novel form of cancer therapy in which medical experts modify T cells in a lab before injecting them into cancer patients’ bodies to enable them to detect and eliminate cancer cells. The immune system is trained to recognize malignant cells by CAR T-cell therapy. The immune response against malignant cells is boosted by CAR T-cell treatment. The market for CAR T-cell therapy is primarily driven by an increase in the demand for suitable therapeutics for the treatment of cancer, favorable reimbursement policies for CAR T-cell therapy medications in some countries, and an increase in consumer awareness of CAR T-cell therapy medications. Additionally, the recent commercialization of CAR-T cell therapy and the surging clinical trial activities are further influencing the market expansion.

In addition, an increase in the incidence of cancer such as leukemia and lymphoma are directly augmenting the demand for CAR T-Cell therapy. According to World Health Organization (WHO), in 2020, the number of leukemia cancer cases is estimated to account for 475 thousand, which is projected to reach 692 thousand patients by the year 2040. Accordingly, the growing prevalence of cancer is fueling the demand for a wide range of diagnosis and treatment alternatives, which, in turn, accelerates the growth of the CAR T-Cell therapy Market. Moreover, the growing investment in research and development, as well as increasing advancements in technology present various lucrative opportunities over the forecasting years. However, the unavailability of skilled professionals and the high cost of developing CAR T-cell therapy are challenging the market growth throughout the forecast period of 2023-2030.

The key regions considered for the Global CAR T-Cell therapy Market study include Asia Pacific, North America, Europe, Latin America, and Middle East & Africa. North America dominated the market in 2022 owing to the increasing regulatory approvals, growing investment in advancing healthcare facilities, and rising technological developments. Whereas, Asia Pacific is expected to grow at the highest CAGR over the forecasting years. The rising prevalence of cancer, increasing research funding for novel therapeutics by government bodies, and growing awareness and increase in approval of novel medications are significantly propelling the market demand across the region.

Major market players included in this report are:
Autolus Therapeutics
Bluebird bio, Inc.
Bristol-Myers Squibb
Caribou Biosciences, Inc.
Cartesian Therapeutics, Inc.
Celgene Corporation
Gilead Sciences, Inc. (Kite Pharma Inc.)
Merck & Co., Inc.
Novartis AG
Pfizer, Inc.

Recent Developments in the Market:
Ø In June 2022, Bristol-Myers Squibb Company announced that the company received the U.S. Food and Drug Administration (FDA) approval for Breyanzi CAR T cell therapy to cure refractory or relapsed large B-cell lymphoma after one prior therapy. The Phase 2 pilot company-sponsored research of a CAR T cell treatment in patients with primary refractory or relapsed LBCL served as the foundation for the approval.
Ø In February 2022, Johnson & Johnson Services, Inc. declared that the U.S. Food and Drug Administration had approved CARVYKTI (ciltacabtagene autoleucel), a BCMA-Directed CAR-T Immunotherapy for the treatment of Patients with Relapsed or Refractory Multiple Myeloma.

Global CAR T-Cell therapy Market Report Scope:
ü Historical Data – 2020 – 2021
ü Base Year for Estimation – 2022
ü Forecast period – 2023-2030
ü Report Coverage – Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
ü Segments Covered – Indication, Drug type, End user, Region
ü Regional Scope – North America; Europe; Asia Pacific; Latin America; Middle East & Africa
ü Customization Scope – Free report customization (equivalent up to 8 analyst’s working hours) with purchase. Addition or alteration to country, regional & segment scope*

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.

The report also caters detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, it also incorporates potential opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Indication:
Lymphoma
Acute Lymphocytic Leukemia
Others

By Drug type:
Axicabtagene Ciloleucel
Tisagenlecleucel
Brexucabtagene Autoleucel
Others

By End-user:
Hospitals
Cancer Treatment Centers

By Region:
North America
U.S.
Canada

Europe
UK
Germany
France
Spain
Italy
ROE

Asia Pacific
China
India
Japan
Australia
South Korea
RoAPAC

Latin America
Brazil
Mexico

Middle East & Africa
Saudi Arabia
South Africa
Rest of Middle East & Africa

Chapter 1. Executive Summary
1.1. Market Snapshot
1.2. Global & Segmental Market Estimates & Forecasts, 2020-2030 (USD Billion)
1.2.1. CAR T-Cell therapy Market, by Region, 2020-2030 (USD Billion)
1.2.2. CAR T-Cell therapy Market, by Indication, 2020-2030 (USD Billion)
1.2.3. CAR T-Cell therapy Market, by Drug type, 2020-2030 (USD Billion)
1.2.4. CAR T-Cell therapy Market, by End user, 2020-2030 (USD Billion)
1.3. Key Trends
1.4. Estimation Methodology
1.5. Research Assumption
Chapter 2. Global CAR T-Cell therapy Market Definition and Scope
2.1. Objective of the Study
2.2. Market Definition & Scope
2.2.1. Industry Evolution
2.2.2. Scope of the Study
2.3. Years Considered for the Study
2.4. Currency Conversion Rates
Chapter 3. Global CAR T-Cell therapy Market Dynamics
3.1. CAR T-Cell therapy Market Impact Analysis (2020-2030)
3.1.1. Market Drivers
3.1.1.1. Increase in the incidence of cancer such as leukemia and lymphoma
3.1.1.2. Favorable reimbursement policies for CAR T-cell therapy medications
3.1.2. Market Challenges
3.1.2.1. Unavailability of skilled professionals
3.1.2.2. High cost of developing CAR T-cell therapy
3.1.3. Market Opportunities
3.1.3.1. Growing investment in research and development
3.1.3.2. Increasing advancements in technology
Chapter 4. Global CAR T-Cell therapy Market Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.2. Porter’s 5 Force Impact Analysis
4.3. PEST Analysis
4.3.1. Political
4.3.2. Economical
4.3.3. Social
4.3.4. Technological
4.3.5. Environmental
4.3.6. Legal
4.4. Top investment opportunity
4.5. Top winning strategies
4.6. COVID-19 Impact Analysis
4.7. Disruptive Trends
4.8. Industry Expert Perspective
4.9. Analyst Recommendation & Conclusion
Chapter 5. Global CAR T-Cell therapy Market, by Indication
5.1. Market Snapshot
5.2. Global CAR T-Cell therapy Market by Indication, Performance – Potential Analysis
5.3. Global CAR T-Cell therapy Market Estimates & Forecasts by Indication 2020-2030 (USD Billion)
5.4. CAR T-Cell therapy Market, Sub Segment Analysis
5.4.1. Lymphoma
5.4.2. Acute Lymphocytic Leukemia
5.4.3. Others
Chapter 6. Global CAR T-Cell therapy Market, by Drug type
6.1. Market Snapshot
6.2. Global CAR T-Cell therapy Market by Drug type, Performance – Potential Analysis
6.3. Global CAR T-Cell therapy Market Estimates & Forecasts by Drug type 2020-2030 (USD Billion)
6.4. CAR T-Cell therapy Market, Sub Segment Analysis
6.4.1. Axicabtagene Ciloleucel
6.4.2. Tisagenlecleucel
6.4.3. Brexucabtagene Autoleucel
6.4.4. Others
Chapter 7. Global CAR T-Cell therapy Market, by End user
7.1. Market Snapshot
7.2. Global CAR T-Cell therapy Market by End user, Performance – Potential Analysis
7.3. Global CAR T-Cell therapy Market Estimates & Forecasts by End user 2020-2030 (USD Billion)
7.4. CAR T-Cell therapy Market, Sub Segment Analysis
7.4.1. Hospitals
7.4.2. Cancer Treatment Centers
Chapter 8. Global CAR T-Cell therapy Market, Regional Analysis
8.1. Top Leading Countries
8.2. Top Emerging Countries
8.3. CAR T-Cell therapy Market, Regional Market Snapshot
8.4. North America CAR T-Cell therapy Market
8.4.1. U.S. CAR T-Cell therapy Market
8.4.1.1. Indication breakdown estimates & forecasts, 2020-2030
8.4.1.2. Drug type breakdown estimates & forecasts, 2020-2030
8.4.1.3. End user breakdown estimates & forecasts, 2020-2030
8.4.2. Canada CAR T-Cell therapy Market
8.5. Europe CAR T-Cell therapy Market Snapshot
8.5.1. U.K. CAR T-Cell therapy Market
8.5.2. Germany CAR T-Cell therapy Market
8.5.3. France CAR T-Cell therapy Market
8.5.4. Spain CAR T-Cell therapy Market
8.5.5. Italy CAR T-Cell therapy Market
8.5.6. Rest of Europe CAR T-Cell therapy Market
8.6. Asia-Pacific CAR T-Cell therapy Market Snapshot
8.6.1. China CAR T-Cell therapy Market
8.6.2. India CAR T-Cell therapy Market
8.6.3. Japan CAR T-Cell therapy Market
8.6.4. Australia CAR T-Cell therapy Market
8.6.5. South Korea CAR T-Cell therapy Market
8.6.6. Rest of Asia Pacific CAR T-Cell therapy Market
8.7. Latin America CAR T-Cell therapy Market Snapshot
8.7.1. Brazil CAR T-Cell therapy Market
8.7.2. Mexico CAR T-Cell therapy Market
8.8. Middle East & Africa CAR T-Cell therapy Market
8.8.1. Saudi Arabia CAR T-Cell therapy Market
8.8.2. South Africa CAR T-Cell therapy Market
8.8.3. Rest of Middle East & Africa CAR T-Cell therapy Market

Chapter 9. Competitive Intelligence
9.1. Key Company SWOT Analysis
9.1.1. Company 1
9.1.2. Company 2
9.1.3. Company 3
9.2. Top Market Strategies
9.3. Company Profiles
9.3.1. Autolus Therapeutics
9.3.1.1. Key Information
9.3.1.2. Overview
9.3.1.3. Financial (Subject to Data Availability)
9.3.1.4. Product Summary
9.3.1.5. Recent Developments
9.3.2. Bluebird bio, Inc.
9.3.3. Bristol-Myers Squibb
9.3.4. Caribou Biosciences, Inc.
9.3.5. Cartesian Therapeutics, Inc.
9.3.6. Celgene Corporation
9.3.7. Gilead Sciences, Inc. (Kite Pharma Inc.)
9.3.8. Merck & Co., Inc.
9.3.9. Novartis AG
9.3.10. Pfizer, Inc.
Chapter 10. Research Process
10.1. Research Process
10.1.1. Data Mining
10.1.2. Analysis
10.1.3. Market Estimation
10.1.4. Validation
10.1.5. Publishing
10.2. Research Attributes
10.3. Research Assumption

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Critical elements of methodology employed for all our studies include:
Data Collection:
To determine the appropriate methods of data collection based on the research objectives, we consider both primary and secondary sources. Primary data collection involves gathering information directly from various industry experts in core and related fields, original equipment manufacturers (OEMs), vendors, suppliers, technology developers, alliances, and organizations. These sources encompass all segments of the value chain within the specific industry. Through in-depth interviews, we engage with key industry participants, subject-matter experts, C-level executives of major market players, industry consultants, and other relevant experts. This allows us to obtain and validate critical qualitative and quantitative information while evaluating market prospects. AI and Big Data are instrumental in our primary research, providing us with powerful tools to collect, analyze, and derive insights from data efficiently. These technologies contribute to the advancement of research methodologies, enabling us to make data-driven decisions and uncover valuable findings.
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Data Analysis:
Our team of experts carefully examine the gathered data using suitable statistical techniques and qualitative analysis methods. For quantitative analysis, we employ descriptive statistics, regression analysis, and other advanced statistical methods, depending on the characteristics of the data. This analysis may also incorporate the utilization of AI tools and big data analysis techniques to extract meaningful insights.
To ensure the accuracy and reliability of our findings, we extensively leverage data science techniques, which help us minimize discrepancies and uncertainties in our analysis. We employ Data Science to clean and preprocess the data, ensuring its quality and reliability. This involves handling missing data, removing outliers, standardizing variables, and transforming data into suitable formats for analysis. The application of data science techniques enhances our accuracy, efficiency, and depth of analysis, enabling us to stay competitive in dynamic market environments.
Market Size Estimation:
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In our forecasting process, we consider various parameters such as economic tools, technological analysis, industry experience, and domain expertise. By taking all these factors into account, we strive to produce accurate and reliable market forecasts. When forecasting, we take into consideration several parameters, which include:
Market driving trends and favorable economic conditions
Restraints and challenges that are expected to be encountered during the forecast period.
Anticipated opportunities for growth and development
Technological advancements and projected developments in the market
Consumer spending trends and dynamics
Shifts in consumer preferences and behaviors.
The current state of raw materials and trends in supply versus pricing
Regulatory landscape and expected changes or developments.
The existing capacity in the market and any expected additions or expansions up to the end of the forecast period.
To assess the market impact of these parameters, we assign weights to each one and utilize weighted average analysis. This process allows us to quantify their influence on the market and derive an expected growth rate for the forecasted period. By considering these various factors and applying a weighted analysis approach, we strive to provide accurate and reliable market forecasts.
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